Engineering Approaches to Age - related Diseases
نویسندگان
چکیده
Age-related bone remodeling cause fragility of the femoral neck, thereby increasing fracture risk in elderly populations. We observed that the femoral necks of simulated young subjects manifested a marked predisposition to undergo yielding, whereas the femoral neck models of elderly subjects were generally more prone to buckling prior to yielding. Another diseases, diabetes mellitus is a ‘21st century epidemic’ affecting 8.3% of the world’s adult population especially the elderly. The degenerative change of glycation occurs at cellular level due to DM is reported to have stiffened the plantar soft tissue and lead to higher ulceration risk. Assessment was performed to investigate the effect of DM on plantar tissue stiffness.
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